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Index > Protein center > GHR(Gene name) > Dog
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  • GHR (Gene name),
  • Growth hormone receptor (Protein name ),  GHR_CANFA from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    GHR;
    Protein name:
    Growth hormone receptor(GH receptor);
    Alternative:
    Somatotropin receptor;
    Organism:
    Dog (Canis familiarisCanis lupus familiaris). 
    General Annotation
    Sub Unit:
    On growth hormone (GH) binding, forms homodimers and binds JAK2 via a box 1-containing domain (By similarity). Binding to SOCS3 inhibits JAK2 activation, binding to CIS and SOCS2 inhibits STAT5 activation.
    Function:
    The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling.
    Subcellular Location:
    Cell membrane Single-pass type I membrane protein On growth hormone binding, GHR is ubiquitinated, internalized, down-regulated and transported into a degradative or non-degradative pathway.
    Protein Attributes:
    Sequence length:
    638
    Sequence:
    50:
    MDLWQLLLTL | AVAGSGSAFS | GSEATPTILG | SASQSLQRVN | PGLGTNSSEK | 
    100:
    PKFTKCRSPE | LETFSCHWTD | GVRHGLKNAG | SVQLFYIRRS | TQEWTQEWKE | 
    150:
    CPDYVSAGEN | SCYFNSSYTS | IWIPYCIKLT | SNGGTVDQKC | FSVEEIVQPD | 
    200:
    PPIGLNWTLL | NISLTGIHAD | IQVRWEPPPN | ADVQKGWIVL | KYELQYKEVN | 
    250:
    ESQWKMMDPV | SATSVPVYSL | RLDKEYEVRV | RSRQRNSEKY | GEFSEALYVT | 
    300:
    LPQMSPFACE | EDFQFPWFLI | IIFGIFGLTM | ILFLFIFSKQ | QRIKMLILPP | 
    350:
    VPVPKIKGID | PDLLKEGKLE | EVNTILAIHD | NYKPEFYNDD | SWVEFIELDI | 
    400:
    DDLDEKTEGS | DTDRLLSNDH | EKSLNILGAK | DDDSGRTSCY | EPDILETDFN | 
    450:
    ASDVCDGTSE | VAQPQRLKGE | VDLLCLDQKN | QNNSPSTDTT | PTTQQPSIIL | 
    500:
    AKENKPRPLL | ISGTESTQQA | AHTQLSNPSS | LANIDFYAQV | SDITLAGSVV | 
    550:
    LSPGQKNKAG | ISPCDMPPEV | ASLCQANFIM | DNAYFCEADA | KKCITVAPHV | 
    600:
    EAESRVEPSF | NQEDIYITTE | SLTTTAGQSG | TTERAVSSEM | PVPDYTSIHI | 
    638:
    IQSPRGLVLN | ATALPLPDKE | FLSSCGYVST | DQLNKIMP
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    SMR:
    UniGene:
    String:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Dog GH receptor
    Cat.:
    E1036h
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    Packing:
    96T
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    ELISA Kit for Dog GH receptor
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    E1036p
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    MSDS:
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    96T
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    ELISA Kit for Dog GH receptor
    Cat.:
    E1036m
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    Packing:
    96T
    ELISA Kit for Dog GH receptor
    Cat.:
    E1036c
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    96T
    ELISA Kit for Dog GH receptor
    Cat.:
    E1036d
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    96T
    ELISA Kit for Dog GH receptor
    Cat.:
    E1036r
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    Packing:
    96T
    ELISA Kit for Dog GH receptor
    MSDS:
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    ELISA Kit for Dog GH receptor
    Cat.:
    E1036b
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    Packing:
    96T
    CLIA Kit for Dog GH receptor
    Cat.:
    U1036d
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    Packing:
    96T
    CLIA Kit for Dog GH receptor
    Cat.:
    U1036r
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Dog GH receptor
    Cat.:
    U1036c
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Dog GH receptor
    Cat.:
    U1036p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Dog GH receptor
    Cat.:
    U1036m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Dog GH receptor
    Cat.:
    U1036b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Dog GH receptor
    Cat.:
    U1036h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Dog GH receptor
    MSDS:
    Please sign in first.
    Polyclonal Antibody for Dog GH receptor
    Cat.:
    P1036Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Dog GH receptor
    Cat.:
    P1036Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Dog GH receptor
    Polyclonal Antibody for Dog GH receptor
    Cat.:
    P1036Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Dog GH receptor
    Polyclonal Antibody for Dog GH receptor
    Polyclonal Antibody for Dog GH receptor
    Polyclonal Antibody for Dog GH receptor
    Monoclonal Antibody for Dog GH receptor
    Monoclonal Antibody for Dog GH receptor
    Monoclonal Antibody for Dog GH receptor
    Monoclonal Antibody for Dog GH receptor
    Monoclonal Antibody for Dog GH receptor
    Monoclonal Antibody for Dog GH receptor
    Monoclonal Antibody for Dog GH receptor
    Monoclonal Antibody for Dog GH receptor
    Protein for Dog GH receptor
    Cat.:
    R1036h
    Price:
    Please sign in first.
    Packing:
    1mg
    Purity:
    >90%
    Protein for Dog GH receptor
    Protein for Dog GH receptor
    Protein for Dog GH receptor
    Protein for Dog GH receptor
    Protein for Dog GH receptor
    Protein for Dog GH receptor
    Protein for Dog GH receptor

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    References
    1. 1.
      "Expression and molecular characterization of the growth hormone receptor in canine mammary tissue and mammary tumors."
      van Garderen E. , van der Poel H.J.A. , Swennenhuis J.F. , Wissink E.H.J. , Rutteman G.R. , Hellmen E. , Mol J.A. , Schalken J.A.
      Endocrinology140:5907-5914(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1; 2; 3; 4 AND 5)
      tissue: Mammary gland.
    2. 2.
      "Gene-specific universal mammalian sequence-tagged sites: application to the canine genome."
      Venta P.J. , Brouillette J.A. , Yuzbasiyan-Gurkan V. , Brewer G.J.
      Biochem. Genet.34:321-341(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 351-373
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